Greenville, N.C. – Dr. Carlos Marroquin, a physician at ECU Health Medical Center and adjunct professor in Surgical Immunology, Transplantation and Surgical Oncology at the Brody School of Medicine at East Carolina University, performed the health system’s first procedure with the Edison® Histotripsy System, a groundbreaking, non invasive technology designed to treat liver tumors using focused ultrasound energy, on April 21, 2026. ECU Health is the first health system in North Carolina east of Winston-Salem to offer this innovative therapy, expanding treatment options for patients with primary and metastatic liver tumors.
“Our patients deserve access to the highest level of care without the burden of traveling long distances for advanced treatment options,” said Jay Briley, president of ECU Health Medical Center. “This technology reinforces our commitment to ensuring that world‑class, innovative care is available right here in eastern North Carolina. I am proud of the team that made this possible.“
The Edison System is the first non‑invasive, non‑thermal, non‑ionizing treatment option for destroying targeted liver tissue with a novel mechanism of action called histotripsy. It delivers sound waves that mechanically break down targeted tissue without incisions, needles, heat or radiation. The procedure is performed on an outpatient basis, offering a new option for patients who prefer a non-invasive approach or who may not be candidates for an invasive surgical approach for many other medical reasons yet have cancer in their liver. Since they would not tolerate an invasive procedure and the associated challenging recovery, histotripsy offers a viable option to treat their tumor. Histotripsy’s unique mechanism of action helps physicians precisely destroy liver tumors while preserving surrounding healthy tissue.
“We are proud to offer cutting-edge treatment options for patients facing liver cancer,” said Dr. Marroquin. “The Edison Histotripsy System enhances our ability to deliver personalized care by giving us a non invasive way to target tumors that may be difficult to remove surgically or to combine with other therapies. This technology represents an advancement in liver tumor care and reflects ECU Health’s commitment to bringing the most promising, patient-centered innovations to eastern North Carolina.”
In North Carolina, incidence and late-stage diagnosis rates of liver cancer are slightly higher than national averages, according to the National Cancer Society. These challenges are even more pronounced in rural and eastern parts of the state, where higher burdens of chronic liver disease and limited access to specialty care contribute to worse outcomes. In addition to primary liver tumors, many patients in the region also face liver metastases from other cancer conditions that similarly lack accessible, non invasive treatment options. Bringing a non-invasive, advanced treatment like histotripsy to ECU Health Medical Center directly addresses these disparities and expands access to lifesaving care for the region.
ECU Health team members that were part of the new procedure include: Carlos Marroquin, MD, Kelly Giordano, RN, Kierra Gainer, RN, Jessie Sbrocco, CST, Paula Boyd, CST, Connor Lawler, DO, Daniel Lavalley, MD, and Ryan Louer, MD.